It seems that the -n option works the way you want:
sublime_text.exe -n file.txt
But the behavior of Windows (not sure what Linux is) is that it creates two instances: one with previously edited files, and the other only with file.txt .
In any case, my own experience: I almost always have at least one instance of ST2 open (I suppose something similar in your case), so in this case it is possible:
ctrl+shift+n creates another instance of ST2, and you can open the file in this (empty).
If you just opened the file (for example, from the command line without -n ), and the ST2 instance was created not only with the open file, but also with some other previously edited files on other tabs - you can just simply drag the file tab and move it outside. Then a new instance of ST2 is created only with this file (i.e. One tab in one window).
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