Try the following:
<asp:Button ID="Button1" UseSubmitBehavior="false"
OnClientClick="javascript:document.getElementById('Button1').disabled = true; __doPostBack('__Page', '');"
onclick="Button1_Click" runat="server" Text="Button" />
It will take place without additional verification of the request.
, onclick:
_doPostBack ('_ Page', 'YOURBUTTONNAME') .