Twisted is not dependent on the full zope. It is simple zope.interface, which is a small module of pure python, packaged separately from all zope.
You can download the version .tar.gzand run the regular one python setup.py install, which should work. Or if your operating system includes a package management system, you can check it for an easy-to-install package. For example, in debian / ubuntu you can do:
apt-get install python-zopeinterface
or even
apt-get install python-twisted
directly.
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