You use it if your code needs to access the DOM.
If you simply configure classes and modules, but do not actually execute them, you do not need to wrap them in a ready-made handler.
However, if you are doing something that requires loading elements (for example, adding event handlers), you need to do this in the ready () event.
EDIT:
: http://jsfiddle.net/ctrlfrk/43n8U/
addHandler , .
( , jsfiddle head, onload, )