How about this?
\documentclass{beamer}
\begin{document}
\begin{frame}
\frametitle{Title}
\begin{tabular}{p{0.4\textwidth}p{0.5\textwidth}}
\begin{itemize}
\item Topic Apple:
\item Topic Watermelon:
\end{itemize} &
\begin{itemize}
\item[] Something to say about it
\item[] Something to say about it
\end{itemize} \\
\end{tabular}
\end{frame}
\end{document}
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