You can use the list view to create a new list that removes the last item.
>>> alist = [[1,2,(3,4)],[5,6,(7,8)],[9,10,(11,12)]]
>>> [x[:-1] for x in alist]
[[1, 2], [5, 6], [9, 10]]
However, if you want to increase efficiency, you can change the list in place:
>>> alist = [[1,2,(3,4)],[5,6,(7,8)],[9,10,(11,12)]]
>>> for x in alist: del x[-1]
...
>>> alist
[[1, 2], [5, 6], [9, 10]]