Vs Web.Config Variable Application Variable

Question

Which is better in terms of performance?

• Access to the global application variable (application ["foo"])

against

• Accessing the AppSetting Variable from web.config

Does .NET use AppSetting variable caching so that it does not access the web.config file every time it is used?

Answer 1

. appSettings . Application , , , . - , , .

appSettings , . AppDomain, . , web.config, AppDomain, , .

Answer 2

appSettings -,

EDIT: , appSettings, Application . , .