The current version of Qt (4.6) does not support Visual Studio 2010:
http://doc.qt.nokia.com/4.6/supported-platforms.html
However, as you can see from this link, Qt 4.7 plans to support it.
Can you use Visual Studio 2008 instead? I used it with the Qt plugin. You might need the full version of VS 2008 - I don’t think you can install the Qt plugin in the Express version.
Visual Studio 2008 , Eclipse Qt QtCreator ( - Qt.) Qt , , , , Visual Studio ( .)