Select 'x86' and I bet it will work;
You most likely have a “x86” link (32-bit) in your project, such as DotTwain. "Any processor" means that the .NET platform will run it as "x64" because you said that everything is in order. Then he tries to load the link, finds it 32-bit and gives a "BadImageFormatException" (usually).
So, you will need a version of DotTwain that was not "ngen-ed", also has a link to the CPU "Any" or releases a separate 64-bit version where all your links are definitely not set to "x86" (you need "any" or "x64").
( , , 32-, 64- DotTwain Atalasoft)
, !