I have an example that shows how to do this in a real-world functional programming book. Chapter 13 first loads some data, then adds it to Excel and creates a graph.
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let chartobjects = (worksheet.ChartObjects() :?> ChartObjects)
let chartobject = chartobjects.Add(400.0, 20.0, 550.0, 350.0)
chartobject.Chart.ChartWizard
(Title = "Area covered by forests",
Source = worksheet.Range("B2", "E" + endColumn),
Gallery = XlChartType.xl3DColumn, PlotBy = XlRowCol.xlColumns,
SeriesLabels = 1, CategoryLabels = 1,
CategoryTitle = "", ValueTitle = "Forests (mil km^2)")
chartobject.Chart.ChartStyle <- 5