The UIImage methods imageNamed: and imageWithContentsOfFile: do slightly different things. imageNamed loads the image into a special system cache, and then future calls with this path will return the image to the cache, and not reload it from disk. imageWithContentsOfFile just loads the image at the path you specify, but does not cache. Multiple calls to imageWithContentsOfFile for the same image will result in multiple copies in memory.
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http://www.alexcurylo.com/blog/2009/01/13/imagenamed-is-evil/