Let's say you have a normal song with two layers, one instrumental and one more vocals. Now let's say that you only have a tool layer. Is it possible to subtract instrumentals and get clean vocals? Will there be a loss? How do I go about doing this particular type of subtractive synthesis?
Using technology (and software), for example: Audacity Vocal Removals I bet you can get what you need. As Daniel and Paolo said, if you can apply sound wave inversion to the original sound wave, you can cancel it (drown out the sound).
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Hypothetically speaking, wonderful things are possible with this idea. In practice, there are too many flaws in the music production process.
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