Sorry, I know this post is a little old, but I could not find another solution for this elsewhere.
This doesn't seem to be related to Vista \ 7, but with the release of Toolkit in February.
IsHitTestVisible = false, , , , . , .
, DataGrid , ( ). , , DataGrid. "", . , - .
, "PreviewKeyDown" e.Handdled = true. - , - , (, ). , , , , - , .