I know this very late, but I thought that it would help others facing the same problem.
I assume you want to fire an SelectedIndexChangedEvent DropDownListthat is already associated with some data!
For example, [C #]
ddlMyDropDown.DataSource = listOfCustomers;
ddlMyDropDown.DataTextField = "CustomerName";
ddlMyDropDown.DataValueField = "CustomerID";
ddlMyDropDown.DataBind();
ddlMyDropDown.CauseValidation = false;
, asp.net( ).. 4.0.