Alternative: xlrd package has a reader. The xlwt package (pyExcelerator plug) has the author. They do a great job with files from the 100s MB; Packages have been widely used for 4 years. Modules of compound documents are aimed at receiving flows of "Workbook" in Excel.xls files and from them as efficiently as possible, but quite universal. Unlike OleFileIO_PL, they do not provide access to the internal properties of the Property streams.
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If you decide to use them and need help, ask in this forum:
http://groups.google.com/group/python-excel
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