The reason is because you are pointing Fromto DoubleAnimations.
If the radius is less than 100 when it MouseLeavehappens, the property Fromwill cause it to jump to 100 and probably cause a MouseEnter. Then you have two competing animations, and the mouse events go crazy when the radius of the ellipse flickers under the cursor.
, From, , , :
<Page xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation" xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml" Title="Window1">
<Canvas>
<Path Margin="15,15,15,15" Fill="Blue">
<Path.Data>
<EllipseGeometry x:Name="MyAnimatedEllipseGeometry" Center="200,100" RadiusX="15" RadiusY="15"/>
</Path.Data>
<Path.Triggers>
<EventTrigger RoutedEvent="UIElement.MouseEnter">
<BeginStoryboard>
<Storyboard>
<DoubleAnimation Storyboard.TargetName="MyAnimatedEllipseGeometry" Duration="0:0:.5" Storyboard.TargetProperty="RadiusX" To="100"/>
<DoubleAnimation Storyboard.TargetName="MyAnimatedEllipseGeometry" Duration="0:0:.5" Storyboard.TargetProperty="RadiusY" To="100"/>
</Storyboard>
</BeginStoryboard>
</EventTrigger>
<EventTrigger RoutedEvent="UIElement.MouseLeave">
<BeginStoryboard>
<Storyboard>
<DoubleAnimation Storyboard.TargetName="MyAnimatedEllipseGeometry" Duration="0:0:.5" Storyboard.TargetProperty="RadiusX" To="15"/>
<DoubleAnimation Storyboard.TargetName="MyAnimatedEllipseGeometry" Duration="0:0:.5" Storyboard.TargetProperty="RadiusY" To="15"/>
</Storyboard>
</BeginStoryboard>
</EventTrigger>
</Path.Triggers>
</Path>
</Canvas>
</Page>
, Storyboard.Duration, , Storyboard . Duration DoubleAnimation - XAML , .