Gdiplus does not seem to support 64-bit operations. Some simple way to still use Gdiplus methods is to split the image into two 32-bit images and work with them separately.
ARGB AARR GGBB 32- ARGB.
, , :
gAARR.DrawLine(new Pen(Color(0,0,255,255), 1, 0, 0, 100, 100);
gGGBB.DrawLine(new Pen(Color(4,0,0,31), 1, 0, 0, 100, 100);
gHigh.DrawLine(new Pen(Color(0,255,4,0), 1, 0, 0, 100, 100);
gLow.DrawLine(new Pen(Color(0,255,0,31), 1, 0, 0, 100, 100);
, (A, R, G, B), . MSDN, Color (R, G, B, A). -, , (R, G, B).
, 2 .