At 9.5 years and older, this would not be possible, because the account under which your instance is running is SYSADM. In addition, the administrator can reset at least the local passwords of the account and access them, which makes it impossible to change the account owner’s account.
However, from 9.7 onwards, the instance owner will no longer have access to the data. One option is up to 9.7. In addition, you can set up an AD account for connections used by your applications. The local administrator can optionally change these credentials.
However, the Administrator ultimately has access to the database files (usually not encrypted). Basically, you can improve the administrative aspect of security.
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