The obvious way is to convert to a list.
batch = random.sample(list(my_deque), batch_size))
But you can avoid creating an entire list.
idx_batch = set(sample(range(len(my_deque)), batch_size))
batch = [val for i, val in enumerate(my_deque) if i in idx_batch]
PS (Ed)
Actually, it random.sampleshould work fine with deques in Python> = 3.5. because the class has been updated in accordance with the Sequence interface.
In [3]: deq = collections.deque(range(100))
In [4]: random.sample(deq, 10)
Out[4]: [12, 64, 84, 77, 99, 69, 1, 93, 82, 35]
! , , , O (n) , m random O (m * n).