You cannot do this in C #, since C # does not have a preprocessor, and the C # compiler, although it supports some syntax that looks like preprocessor syntax, is processed by the compiler itself, and the compiler does not support include directives.
Also, if even one file actually requires 20 using statements, it sounds to me as if you put too much responsibility in one class. Perhaps this will be better served by refactoring and restructuring the code base, thereby reducing the number of directives required?
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