If the image is 26112 x 20480 with three channels, one byte per channel, uncompressed data takes up 3 x 26112 x 20480 bytes, which is about 1.5 gigabytes. A JPEG file can be much smaller because it uses lossy compression, but it does not have an OpenCV representation.
(, ) , Jpegtran, , d OpenCV . , DCT- 8x8, , OpenCV .
, OpenCV, numpy - . , , , , , . , . mmap , , OpenCV, .