If I understand correctly what you want, you probably want to use this selector.
Original CSS that makes grayscale
.select2-default {
color: #f00 !important;
}
Change your preferred placeholder color
.select2-default {
color: #f00 !important;
}
Specific color placeholder (using id)
#s2id_<elementid> .select2-default {
color: #f00 !important;
}
Replace original inputor selectid
In this case
#s2id_leadadd_mode_of_enq .select2-default {
color: #f00 !important;
}
, , <option></option>, , .
<select id="leadadd_mode_of_enq" name="leadadd_mode_of_enq" class="select2 req_place" data-select-search="true" placeholder="Mode of enquiry">
<option></option>
<option value="1">Opt1</option>
<option value="2">Opt2</option>
</select>