25%? I would not worry about this if you have no precedent for your page where your users will be so far away.
Now, 75% -125%, you can consider this. Typically, your page will work just fine at other zoom levels. If this is not the case, probably because you have hard-coded something that you shouldn't have. (For example, you can assume that text on a particular line will never be wrapped. This is not a good assumption. Different devices use different fonts, which in some cases can lead to text wrapping.) In these cases, make sure that only if necessary set dimensions to specific values. Let the page be as large as possible.
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