Yes, you can filter several types using the search API or the MQL reader API.
For a search API that looks like this :
filter=(any type:/music/musical_group type:/people/person type:/location/citytown)
This filter reports that it limits the results according to one of three types.
In the MQL Read API, you can filter several types like this :
[{ "id": null, "name": null, "type": [], "name~=": "London", "type|=": [ "/people/person", "/location/citytown", "/music/musical_group" ] }]
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