It is possible, but only for one separate compilation. For example, the following compiles a single file for Firefox:
<set-property name="user.agent" value="gecko"/> <add-linker name="sso"/>
Since GWT generates browser versions, this means that only one browser is supported in the compiled file. If you need other browsers, change user.agent and compile again. Please note that if you want to support multiple browsers, you need to provide the correct version to the user, something GWT does for you if you use the normal compilation process. So I'm not sure if this is what you really want.
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