No, nothing at all , unless you have the habit of using the class attribute:
[class="class1 class2"] { }
instead:
.class1.class2 { }
which, of course, is a terrible practice.
Also, although your question is not tagged with javascript , note that if only the first instance of the class is deleted and an unlimited number is added, say:
function addClass(element, cls) { element.className += ' ' + cls; }
but
function removeClass(element, cls) { return element.className.replace(cls, ' '); }
this will cause problems more than one.
source share