Zalgo is waiting outside the wall.
You want to filter out a combination of characters, such as diacritics, listed here .
You should get away with a simple character class pattern matching, i.e.:
fooString.replace(/[\u0300-\u036f\u0483-\u0489\u1dc0-\u1dff\u20d0-\u20ff\ufe20-\ufe2f]/, "");
If you want to limit the content to one combination per character (not so that it really mitigates all the negative side effects), you could simply use
fooString.replace(/([\u0300-\u036f\u0483-\u0489\u1dc0-\u1dff\u20d0-\u20ff\ufe20-\ufe2f])[\u0300-\u036f\u0483-\u0489\u1dc0-\u1dff\u20d0-\u20ff\ufe20-\ufe2f]*/, "$1");
EDIT: Added a number of other combined character ranges. This is most likely still not exhaustive.
source share