All IDEs on the market have the first three of your requirements:
- Intelisense
- Step by step debugging.
- Ease of use and training IDE
For the wysiwyg part, Dreamweaver, VisualStudio, and DashCode (part of the Mac OS X dev tools) are the only ones I know that have this functionality. However, I’m not sure about Dreamweaver’s ability to create and work with HTML5, CSS3 or even JavaScript (I haven’t used it in years), and DashCode (starting from version 2.02) only creates iPhone / iPod Touch apps. I can not say for VisualStudio.
I saw Radi a few weeks ago, but I have not tried. He seems to be focusing on "WOW!" however, part of the whim of HTML5.
I did not know about the real efforts in this area, it might be worth seeing how Real Studio was quite good in the late 90s.
But no matter what tool you use, the “HTML5 application” is nothing more than a bunch of HTML / CSS / JS files. It can be created with almost any program editor / IDE, and the nickname "HTML5" is often just an empty word, since most of what makes it cool (JS API, CSS3 animations, ...) is available for any web page, HTML5, HTML4, XHTML1 ...
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