The .apk file must be signed.
Eclipse automatically generates a .apk signed with a debug key in bin / YourApp.apk. It is normal to use this file for testing, but you should not give this .apk to clients or end users, because you will not be able to update this application in the future.
If you intend to publish this .apk to your customers, you must use your own key to sign .apk. Read: Signing Your Applications
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