This perlmonks thread has information about Catalyst (which is Perl's most advanced / powerful web development infrastructure) in the security context.
For a general comparison, some of them are linked in the Comparisons section of the Web Framework / Perl5 Wiki
In addition, remember that the main security problem is the developer - you can write code with a hole in the most secure environment if you do not have the right security-oriented look in your development (this was the main point for us in our safe web development training , and I agree).
Also, as per Brianβs request in a comment, this is a couple of useful general web security links in Perl:
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