You can create a 1x1 transparent pixel image and place it in a div that has a sprite. For instance:
<style type="text/css"> #linkContainer {background:url(images/sprite.gif) 0 50 no-repeat} //sprite selection width/height, set cursor to pointer so users know its a link #linkContainer img {width:50px;height:25px;cursor:pointer} <style> <div id="buttonContainer"><img src="pixel.gif" alt="Your alt text"></div>
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