From my point of view, vendor-specific platforms, such as AJAX management tools, benefit only from ecosystems and examples published by this particular vendor (and third-party developers). In this case, only Microsoft and ASP.NET developers.
In the case of vendor agnostic tools such as jquery, you benefit from all types of web developers who publish blogs and articles: ruby, python, coldfusion, asp.net, etc.
So, my voice is usually used for jQuery, unless there is a specific reason (i.e. specific control) that I absolutely must use from ajax management tools. And even in those cases, most likely someone has a jquery plugin that will be equivalent.
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