Warning, the answers above are outdated and misleading. Just set up your project with CMake, like opencv 2.x. Then you just install CMake to add $ OPENCV_LIBS as a library for communication, and you're done. In qt creator, file -> open project and open the file CMakeLists.txt, presto.
Do not use qmake or pro files unless you really want QT gui. Even then, first look at the QT samples in opencv 2.2+, I think they use cmake to handle the qt interface.
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