You are looking for full-text indexing, this allows you to perform more complex queries than regular expressions or how.
Check out this article for quick reference, instructions for SQL Server 2000, where it’s a little harder to set up than in 2005 or 2008.
Relevant quote:
With full-text searching, you can perform many other types of search:
* Two words near each other
* Any word derived from a particular root (for example run, ran, or running)
* Multiple words with distinct weightings
* A word or phrase close to the search word or phrase
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