I had the same problem after setting up the environment in Windows 10. I have Python 3.6.2 x64 installed as my default Python distribution and it is in my PATH, so I can run cmd from the command line.
I installed PyQt5 ( pip install pyqt5 ) and Spyder ( pip install spyder ), which both installed without error and included all the necessary dependencies.
To run Spyder, I created a simple Python script (Spyder.py):
# Spyder Start Script from spyder.app import start start.main()
Then I created a Windows batch file (Spyder.bat):
@echo off python c:\<path_to_Spyder_py>\Spyder.py
Finally, I created a shortcut on the desktop that launches Spyder.bat, and updated the icon to the one I downloaded from the Spyder github project.
Works like a charm for me.
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