Find the complete solution here on how to display the image when you hover over it. It uses 'motion_notify_event' to detect when the mouse is above the scatter point (hover). If so, it displays an annotation of the image with the corresponding image next to the overhanging scattering point.
import matplotlib.pyplot as plt from matplotlib.offsetbox import OffsetImage, AnnotationBbox import numpy as np; np.random.seed(42) # Generate data x, y for scatter and an array of images. x = np.arange(20) y = np.random.rand(len(x)) arr = np.empty((len(x),10,10)) for i in range(len(x)): f = np.random.rand(5,5) arr[i, 0:5,0:5] = f arr[i, 5:,0:5] =np.flipud(f) arr[i, 5:,5:] =np.fliplr(np.flipud(f)) arr[i, 0:5:,5:] = np.fliplr(f) # create figure and plot scatter fig = plt.figure() ax = fig.add_subplot(111) line, = ax.plot(x,y, ls="", marker="o") # create the annotations box im = OffsetImage(arr[0,:,:], zoom=5) xybox=(50., 50.) ab = AnnotationBbox(im, (0,0), xybox=xybox, xycoords='data', boxcoords="offset points", pad=0.3, arrowprops=dict(arrowstyle="->")) # add it to the axes and make it invisible ax.add_artist(ab) ab.set_visible(False) def hover(event): # if the mouse is over the scatter points if line.contains(event)[0]: # find out the index within the array from the event ind, = line.contains(event)[1]["ind"] # get the figure size w,h = fig.get_size_inches()*fig.dpi ws = (event.x > w/2.)*-1 + (event.x <= w/2.) hs = (event.y > h/2.)*-1 + (event.y <= h/2.) # if event occurs in the top or right quadrant of the figure, # change the annotation box position relative to mouse. ab.xybox = (xybox[0]*ws, xybox[1]*hs) # make annotation box visible ab.set_visible(True) # place it at the position of the hovered scatter point ab.xy =(x[ind], y[ind]) # set the image corresponding to that point im.set_data(arr[ind,:,:]) else: #if the mouse is not over a scatter point ab.set_visible(False) fig.canvas.draw_idle() # add callback for mouse moves fig.canvas.mpl_connect('motion_notify_event', hover) plt.show()

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