You need to do eventbus.subscribe(this.Method1.bind(this));
Since you are linking the method to run elsewhere, you are sure to make sure in which area it will work. Forcing binding to this will ensure that an instance of Class1 is used.
EDIT: since ES6 allows you to perform the functions of arrows, you can also do eventbus.subscribe(() => this.Method1()); as it was reviewed by @torazaburo
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