Definitely - Che uses Docker under the hood as a way to create replicable and portable environments, but the code that was edited in Che translates into a repo like any other. Therefore, if you have a CI build / install system to pull these changes from the repo and deploy a monolithic application that will work anyway.
To configure it, you will need to create a Docker file that matches your runtime. You can find examples of most environments on Dockerhub and there are only a couple of things you need to add to make the container “ready”.